VITIX® - a new treatment for vitiligo?
KU Schallreuter and H Rokos
Int J Dermatol 2005, 44: 969-970
In summary, our results show that the plant extract formulation from Cucumis melo (Vitix®) has no pseudocatalase capacity under in vitro or in vivo conditions. Moreover, there was no significant improvement in facial vitiligo after 4 months of treatment.
FT-Raman spectra of H2O2 following the O-O stretch at 875 cm-1 over time. A comparison of H2O2 removal by Vitix® and pseudocatalase PC-KUS (100 mg of the creams were mixed with 25 μl of 30% H2O2; the first spectra were measured after 3 minutes).
a) Vitix® (native
Form), b) Vitix® (crushed microspheres), c) Pseudocatalase PC-KUS, d) Vehicle alone (pseudocatalase base cream).
Note the rapid degradation of H2O2 by PC-KUS compared to the minimal removal even after 24 hours with Vitix® or with vehicle alone H2O2.