VITIX® - a new treatment for vitiligo?
KU Schallreuter and H Rokos
Int J Dermatol 2005, 44: 969-970
In summary, our results show that the plant extract formulation
from Cucumis melo (Vitix®) has no pseudocatalase capacity under
in vitro or in vivo conditions. Moreover, there was no
significant improvement in facial vitiligo after 4 months of
FT-Raman spectra of H2O2 following the
O-O stretch at 875 cm-1 over time. A comparison of H2O2 removal
by Vitix® and pseudocatalase PC-KUS (100 mg of the
creams were mixed with 25 μl of 30% H2O2;
the first spectra were measured after 3 minutes).
a) Vitix® (native Form),
b) Vitix® (crushed microspheres),
c) Pseudocatalase PC-KUS, d) Vehicle alone
(pseudocatalase base cream).
Note the rapid degradation of H2O2
by PC-KUS compared to the minimal removal even after 24
hours with Vitix® or with vehicle alone H2O2.